Vaccination Adjuvant Works By Killing Cells: Cause of Autoimmune Disorders?

A new Nature Medicine study may provide insight into why there's so much autoimmune disease today. Have the authors unintentionally pointed to the smoking gun that even vaccinators must acknowledge?

by Heidi Stevenson

29 July 2011

Adjuvants are known to increase the ability of vaccines to cause the immune system to make antibodies. Aluminum has been used because it's particularly effective. However, how it works was unknown until a study just published in the journal Nature Medicine. What they found is quite disturbing. Aluminum in vaccines causes cell death, but not of a normal sort, as in apoptosis.

This may be the explanation for much of the autoimmune disease that's experienced by so many people today. Freestanding DNA and other bits of cells are not normal.

In apoptosis, cells die from the inside. It's brought about by processes inside the cell, resulting in controlled dissolution of all parts, including the DNA. Cells that die through apoptosis form cell fragments that phagocytic cells can recognize and engulf easily.

However, in the case of cell death from the vaccine adjuvant, aluminum, the cell comes apart, releases DNA and other cell bits, and cannot be cleaned up easily.

Abnormal cell death is called necrosis. Cells neither break down in a controlled manner, nor do they send the appropriate signals for cleanup. This kind of cell death is called necrosis, and it's what can result in gangrene. (See Wikipedia's discussion on necrosis for a good discussion on the topic.)

An autoimmune disorder is a result of damage caused by an immune system that's gone awry, attacking part of its own body. Rheumatoid arthritis is a prime example. It occurs when the autoimmune system attacks cartilage.

Possible Mechanism for Causing Autoimmune Disorders

What might be happening when cells are killed by aluminum in vaccines? Bits of cells are floating around inside the body without the proper signals sent to trigger a normal cleanup. Unlike surface injuries, these cells cannot be isolated with coagulation.

As a result, the immune system may see these bits as invaders and initiate the immune system to create antibodies.

It's probable that rheumatoid arthritis is caused in a similar manner when squalene is used as an adjuvant. Though cell death is not a factor, squalene is primarily collagen, the substance that makes up cartilage.

It's well known that injecting collagen causes rheumatoid arthritis in mice. Though it goes by the coy name of adjuvant arthritis, mice injected with collagen develop a condition that's indistinguishable from rhematoid arthritis. It's done to create sick animals on which to study treatments for rheumatoid arthritis.

It's beyond comprehension that researchers, doctors, and government agencies deny that squalene could be dangerous. And now, with the information reported by lead author Thomas Marichal in "DNA released from dying host cells mediates aluminum adjuvant activity", we have a strong indication of what may be causing so much autoimmune disease today.

Is it possible that the action that strengthens the immune response to vaccines—cell death caused by aluminum adjuvant—also causes antibodies to be developed against bits of cells produced by necrosis? Could the necrotic tissue also be seen as an invader, so that antibodies are created against it?

Don't hold your breath for studies that document it. If we do see any, the researchers will certainly be subjected to the same sort of character and career assassination that happened to Andrew Wakefield. Nonetheless, let's hope that these studies are done. Otherwise, we're headed for a world full of people who are unable to approach their potential because of illness, facing shortened lifetimes of misery.

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